The non-FLAG-tagged LEDGF/p75 IBD mutant was detected only with an anti-LEDGF/p75 MAb, while the FLAG-tagged LEDGF/p75 CR2 mutant, lacking the epitope detected from the anti-LEDGF/p75 MAb, was detected only from the anti-FLAG antibody

The non-FLAG-tagged LEDGF/p75 IBD mutant was detected only with an anti-LEDGF/p75 MAb, while the FLAG-tagged LEDGF/p75 CR2 mutant, lacking the epitope detected from the anti-LEDGF/p75 MAb, was detected only from the anti-FLAG antibody. capability of LEDGF/p75. These results clearly indicated

Hence, the anti-aggregatory substances are particular toward stress replies induced by aggregated -syn and offer indirect proof for an operating role of -syn aggregation along the way of MT retraction

Hence, the anti-aggregatory substances are particular toward stress replies induced by aggregated -syn and offer indirect proof for an operating role of -syn aggregation along the way of MT retraction. Open in another window FIGURE 5. Inhibition of -synuclein aggregation