These engineered receptors usually contain a monoclonal antibodyderived single-chain variable fragment (scFv) that confers specific binding to a tumor antigen

These engineered receptors usually contain a monoclonal antibodyderived single-chain variable fragment (scFv) that confers specific binding to a tumor antigen. stems from recent innovations in the development of CARs. First-generation CARs comprised an antibody-derived scFv followed by hinge, transmembrane, and

However, upon site-specific fork arrest (Figure 4B, right panelcartoon), the intensity of the Y-arc is predicted to be reduced and an intense spot is predicted on the Y-arc, corresponding to the position of arrested forks

However, upon site-specific fork arrest (Figure 4B, right panelcartoon), the intensity of the Y-arc is predicted to be reduced and an intense spot is predicted on the Y-arc, corresponding to the position of arrested forks. == Figure 4. arrest and