Entirely, CR cells were improbable to possess arisen simply by ALK\dependent mechanisms. To discover novel signaling pathways linked to crizotinib\acquired resistance, we screened a 640 FDA\approved medication collection for medication efficacy in CR and parental pool cells. least fifty percent
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6.0; San Diego, CA, USA). 2.6. A non-cancerous oesophageal primary cells NOK2101, was used to determine the specificity of the aspirin analogues and cytotoxicity assays revealed that analogues PN528 and PN529 were selectively toxic to cancer cell lines, whereas PN508,