1-Step Ultra TMB-ELISA Substrate Solution (Thermo Fisher Scientific, 34028)

1-Step Ultra TMB-ELISA Substrate Solution (Thermo Fisher Scientific, 34028). F. Endoxifen E-isomer hydrochloride B cells; Data 7. Panel G. Ki67. elife-87281-fig1-figsupp4-data1.zip (79K) GUID:?50B3056C-B975-4BF6-B6A9-6DD56DFF9DA7 Figure 1figure supplement 6source data 1: Data 1. Panel A. Spleen Tregs; Data 2. Panel B. Spleen B cells; Data 3. Panel C. Lymph node Tregs; Data 4. Panel D. Lymph node B cells. elife-87281-fig1-figsupp6-data1.zip (45K) GUID:?E7845BE3-8E61-43FE-8F74-DFAF78EBBC7C Figure 1figure supplement 7source data 1: Data 1. Panel B. Pre B Cells; Data 2. Panel C. Pre-pro/pro B cells. elife-87281-fig1-figsupp7-data1.zip (23K) GUID:?26F38FE3-FEF9-4222-ABD5-405C6CE7D6C0 Figure 2source data 1: Data 1. Panel C. Endoxifen E-isomer hydrochloride B220hi apoptosis; Data 2. Panel D. B220lo apoptosis. elife-87281-fig2-data1.zip (22K) GUID:?B82D9A85-A56F-4FE7-9642-9BBE46AAD0B6 Figure 2figure supplement 1source data 1: Data 1. Panel A. Blood B cell apoptosis; Data 2. Panel B. Spleen B cell apoptosis; Data 3. Panel C. Lymph node B cell apoptosis. elife-87281-fig2-figsupp1-data1.zip (34K) GUID:?4907957A-7177-4040-861B-1677097EF592 Figure 3source data 1: Data 1. Panel B. Time course CD45 cell number; Data 2. Panel C. Time course % B220 cells. Data 3. Panel D. Time course B cell number; Data 4. Panel E. Time course % Foxp3 cells; Data 5. Panel F. Time course Treg cell number; Data 6. Panel H. % Mature B cells; Data 7. Panel I. % Immature T1 B cells. elife-87281-fig3-data1.zip (81K) GUID:?C7146A15-7E56-4ADF-B08A-DEE1B340E661 Figure 3figure supplement 1source data 1: Data 1. Panel A. Serum IgG; Data 2. Panel B. Serum IgM; Data 3. Panel C. Serum IgA; Data 4. Panel D. Serum IgE. elife-87281-fig3-figsupp1-data1.zip (45K) GUID:?09A0C2C4-48D3-4D09-9534-53CC8B41BC9B Figure 3figure supplement 2source data 1: Data 1. Panel A. Spleen weight. elife-87281-fig3-figsupp2-data1.zip (11K) GUID:?CBE52AF2-85FF-4A5B-A638-CCA85CACEF35 Figure 4source data 1: Data 1. Panel A. CD4 T-cells; Data 2. Panel B. CD8 T-cells; Data 3. Panel C. Ki67; Data 4. Panel D. CD4 T-cell activation; Data 5. Panel E. CD8 T-cell activation. elife-87281-fig4-data1.zip (57K) GUID:?DFFC4FF6-6438-4406-91E6-33B0CE9FBA92 Figure 4figure supplement 1source data 1: Data 1. Panel A. BM CD4 T-cell; Data 2. Panel B. BM CD8 T-cell; Data 3. Panel D. THY Tregs; Data Endoxifen E-isomer hydrochloride 4. Panel E. THY CD4+CD8- T-cell; Data 5. Panel F. THY CD8+CD4- T-cell; Data 6. Panel G. THY CD4+CD8+ T-cell; Data 7. Panel H. Spleen CD4 T-cell; Data 8. Panel I. Spleen CD8 T-cell; Data 9. Panel J. Lymph node CD4 T-cell; Data 10. Panel K. Lymph node CD8 T-cell. elife-87281-fig4-figsupp1-data1.zip (136K) GUID:?0CE37A60-E8B3-42C4-B9EF-9CF015E9F358 Figure 4figure supplement 2source data 1: Data 1. Panel A. BM T-cell Ki67; Data 2. Panel B. Spleen T-cell Ki67; Data 3. Panel C. Lymph Nodes T-cell Ki67. elife-87281-fig4-figsupp2-data1.zip (34K) GUID:?F3BCAA0D-9B09-4808-BCFD-909D44697EB3 Figure 4figure supplement 3source data 1: Data 1. Panel A. CD4 T-cells; Data 2. Panel B. CD8 FGF14 T-cells; Data 3. Panel C. Ki67. elife-87281-fig4-figsupp3-data1.zip (34K) GUID:?2D2FE57C-BAB2-4770-848F-2559D4EB4352 Figure 5source data 1: Datat 1. Panel C. CD4 T-cells; Data 2. Panel D. CD8 T-cells; Data Endoxifen E-isomer hydrochloride 3. Panel E. B cells; Data 4. Panel G. CD4 T-cells; Data 5. Panel H. CD8 T-cells; Data 6. Panel I. B cells. elife-87281-fig5-data1.zip (70K) GUID:?A52C0660-AA7E-4FAA-884D-45E8DE025930 Figure 6source data 1: Data 1. Panel B. Tregs; Data 2. Panel C. CTLA-4; Data 3. Panel E. B cells; Data 4. Panel F. CD4 T-cell activation; Data 5. Panel G. CD8 T-cell activation; Data 6. Panel I. GranzymeB in CD45; Data 7. Panel J. GranzymeB in CD4; Data 8. Panel K. GranzymeB in CD8. elife-87281-fig6-data1.zip (91K) GUID:?6F3A1148-91A3-497E-8222-3A216F56EFBE Figure 6figure supplement 1source data 1: Data 1. Panel A. Mutant soluble hCTLA-4-Ig blocking of anti-CTLA-4/ADC; Data 2. Panel B. Mutant soluble hCTLA-4-Ig neutralization of anti-CTLA-4/ADC. elife-87281-fig6-figsupp1-data1.zip (24K) GUID:?325C9E08-9F99-474C-BFD9-BEDB516A7B66 Figure 6figure supplement 2source data 1: Data 1. Cytokine production Endoxifen E-isomer hydrochloride in T-cells. elife-87281-fig6-figsupp2-data1.zip (12K) GUID:?2EBE321C-E899-4663-9625-F155E2027B83 Figure 7source data 1: Data 1. Panel A. Elisa binding; Data 2. Panel D. Tregs; Data 3. Panel E. B cells;.