Our observation the fact that marked upsurge in Sox2 protein level in RU cells after YB-1 knockdown didn’t induce detectable Sox2 transcription activity is commensurate with our prior observation, where enforced appearance of Sox2 in MCF7 and ZR751 using an retroviral Sox2 appearance vector also didn’t induce detectable Sox2 transcription activity [16]

Our observation the fact that marked upsurge in Sox2 protein level in RU cells after YB-1 knockdown didn’t induce detectable Sox2 transcription activity is commensurate with our prior observation, where enforced appearance of Sox2 in MCF7 and ZR751 using an