S4C- S4D, Fig. decreased cell growth. Proteomics and metabolomics exposed that HSP60 knockdown advertised Warburg-like phenotypes with enhanced glycolysis and 8-Hydroxyguanosine decreased mitochondrial activity. Consistent with this getting, isotope tracing showed 8-Hydroxyguanosine the metabolic circulation from glycolysis to TCA was
Studies were performed in SPF facilities at the University of Edinburgh under licence PPL 70/8102 and at the University of Glasgow under PPL 60/4442
Studies were performed in SPF facilities at the University of Edinburgh under licence PPL 70/8102 and at the University of Glasgow under PPL 60/4442. PFKs. The compounds cross the blood brain barrier and single day oral dosing cures parasitaemia in